Cryo electron microscopy (cryo-EM) has become an effective and straightforward approach to determine the structure of macromolecules in solution, trapped within a thin film (a few tens of nanometres) vitrified …
Mohamad HARASTANI has defended his PhD thesis entitled “Image analysis method development for in vitro and in situ cryo electron tomography studies of conformational variability of biomolecular complexes: case of …
DNA packaging within viruses, chromosomes or nano-devices leads to extremely compact assemblies where not only high density but also very high curvature prevail. Yet DNA is a rather stiff filament, …
RNA viruses are a family of infectious agents with sometimes dramatic health and economic consequences such as those we are currently experiencing. Over the course of a life cycle, viral …
Maelenn CHEVREUIL has defended her PhD thesis entitled Self-assembly and disassembly dynamical phenomena in icosahedral viruses under the supervision of Stéphane BRESSANELLI and Guillaume TRESSET on February 24, 2020. The …
In Eukaryotes, DNA is regularly wound into a left-handed super-helix around the histone octamer to form a chain of nucleosomes. Atomic structures have been obtained by crystallography of engineered nucleosomes. …
In collaboration with the Institute of Integrative Biology of the Cell (I2BC), the Laboratoire Léon Brillouin and the European Synchrotron Radiation Facility, our team has elucidated the nonequilibrium self-assembly dynamics …
Jacques Dubochet, Joachim Frank and Richard Henderson have been awarded the 2017 Nobel prize for Chemistry “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution” a …
On the occasion of the retirement of Françoise Livolant, the Laboratoire de Physique des Solides (LPS) and the Laboratoire de Physique Théorique et Modèles Statistiques (LPTMS) are organising an international …
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